N,N-Dimethylacetamide Significantly Attenuates LPS- and TNFα-Induced Proinflammatory Responses Via Inhibition of the Nuclear Factor Kappa B Pathway
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چکیده
منابع مشابه
Inhaled nitric oxide attenuates acute lung injury via inhibition of nuclear factor-kappa B and inflammation.
The effect of inhaled nitric oxide (NO) on inflammatory process in acute lung injury (ALI) is unclear. The aims of this study were to 1) examine whether inhaled NO affects the biochemical lung injury parameters and cellular inflammatory responses and 2) determine the effect of inhaled NO on the activation of nuclear factor-kappa B (NF-kappa B) in lipopolysaccharide (LPS)-induced ALI. Compared w...
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Ellagic acid is a naturally occurring polyphenolic compound which is found in many fruits, nut galls and plant extracts. In the present study, we explored the ability of ellagic acid to modulate LPS response using macrophage-mediated inflammatory conditions and acute lung injury (ALI). Methods and Results: First, we found that ellagic acid reduced tumor necrosis factor-α (TNF-α), interleukin-6 ...
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ژورنال
عنوان ژورنال: Molecular Medicine
سال: 2016
ISSN: 1076-1551,1528-3658
DOI: 10.2119/molmed.2016.00017